How is prediabetes defined with regards to fasting blood glucose (FBG)?

The definition of prediabetes in relation to fasting blood glucose (FBG) levels indicates that an individual is classified as prediabetic if their FBG is greater than 100 mg/dL but less than 126 mg/dL. This range identifies individuals who have elevated blood sugar levels that are not high enough to be classified as diabetes but still indicate a risk for developing the condition.

The rationale behind this classification is based on the understanding that FBG measurements between these values reflect an impaired glucose metabolism. Those with an FBG level in this range should be monitored and may benefit from lifestyle changes, such as improved diet and increased physical activity, to potentially prevent the progression to type 2 diabetes.

In this context, a FBG of exactly 100 mg/dL does not establish prediabetes; rather, it marks the lower end of the prediabetes range. A FBG below 100 mg/dL is considered normal, and a FBG above 126 mg/dL is indicative of diabetes, not prediabetes. Thus, the correct definition encompasses the specified range in order to effectively identify individuals at risk.