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A T-test is specifically designed to determine whether there is a statistically significant difference between the means of two groups. This makes it particularly useful in scenarios where you need to compare the performance, attitudes, or outcomes of two distinct populations or treatment conditions.

For instance, if researchers wanted to compare the effectiveness of a specific intervention on a control group versus a treatment group, a T-test would provide insights into whether the differences observed are due to the intervention or just random variation. By focusing on the means of these two groups, researchers can draw conclusions that inform practice or further research.

The other scenarios involve different statistical methods: analyzing a single group once would typically require a different test like a one-sample T-test or a confidence interval; comparing population averages could involve techniques such as ANOVA if more than two groups are involved; analyzing correlation data would necessitate the use of different methods such as Pearson's correlation coefficient. Each of these situations requires distinct statistical approaches tailored to their specific data structures and research questions.